Friday 31 May 2024

Parkinson's Disease Treatments

 


Well Friday has arrived and that means time for a little more about Parkinson’s Disease, still looking at medication and treatment.

The aim of drug treatment is to keep the patient active, independent and free of handicap. Easier said than done.

Just raising the amount of medication, one takes is not necessarily the answer or in the patient’s best interest. Due of course to the side effects, no point in having the symptoms disappear if one is left in a zombie like condition.

As mentioned before levodopa can be a big help with symptoms often restoring the level of dopamine closer to normal which can help with the symptoms.

However, with Parkinson’s some brain cells containing a substance called acetyl choline react to the lack of dopamine by increasing activity. This of course makes the symptoms worse not better. Treatment with anti-cholinergic drugs can help with that.

These two drug groups kind of come at the problem from two ends, hopefully tending to tilt more towards what would be considered normal.

As the disease progresses it is common to find oneself on a number of medications by having to take as many as five different medications to help one manage some kind of normalcy.

Naturally many would be concerned about taking large numbers of tablets worrying how they are reacting with each other, or if they are accumulating in the body. Neither of these fears are realistic as the drugs do not inter-react generally speaking there are always the chance of it happening, but it is extremely rare and when this happens it is well-recognised and quickly picked up.   

Nearly all the drugs used are broken down destroyed in the body within 24 hours, so no risk of a build up in the body. There may be changes in the way the body’s nervous system responses to the medication over time, in general we become more sensitive to them which causes the change in response.

10 comments:

  1. Both the build up and the non-reactive nature of the drugs is new to me. Great info!

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  2. I would imagine trying to find the right combination of drugs takes a while...and then your body can change it's reaction over time. Whew! Sounds complicated. I hope they can find what works the best for you.

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    1. At the moment what I am on is working well for me

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  3. It sounds like even if you find the right combination, it changes over time. If every body handles it differently, it must be hard to come up with the right dose for every person, then as you change, the drugs change. Complicated to say the least.

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  4. I did confirm this week that my SIL's mother has Parkinson's, so I am more attentive than ever to these updates.
    Blessings, Jo-Anne!

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    1. Sorry to hear about your SIL's mother this is a rotten condition you have, but pleased you like these posts

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  5. A lot has happened in medicine and drug research in recent years. That is very good.

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    Replies
    1. So very true, we have come a long way, with still a long way to go

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